CLINICAL AND LABORATORY FEATURES RELATED TO MORTALITY RATE OF BLOOD STREAM INFECTION PATIENTS ADMITTED TO NATIONAL HOSPITAL FOR TROPICAL DISEASES (7/2017 - 6/2020)

Tóm tắt

Objectives: The aim of this study was to evaluate clinical and laboratory features related to mortality rate of blood stream infection patients admitted to National hospital for Tropical Diseases.

Subjects and methods: A cross - sectional study was conducted among patients diagnosed blood stream infection from 7/2017 to 6/2010 in National hospital for Tropical Diseases. A total of 200 patients with clinical sign, symptoms of sepsis and positive blood culture were included in the study. Univariate and multivariate logistic regressions were used to identify independent prognostic factors for mortality.

Results: Of 200 blood stream infection patients, 131 patients were male (65.5%); 150 patients (75%) had comorbidities, the most common diseases are cardiovascular diseases (26%), diabetes mellitus (23.5%), hepatic diseases (18.5%) and alcoholism (13%). E. coli (32%), S.aureus (28.5%) are the most frequent causes indentified in blood culture. There were 44 died (22%) and 156 survived (78%). Platelet < 100G/L (OR = 3.61), rAPTT > 1.25 (OR = 6.26), shock (OR = 71.99), the number of organ dysfunctions ≥ 3 (OR = 4.06) were independent prognostic factors.

Conclusion: Septic shock, multiple organ failure and thrombocytopenia are the prognostic factors for mortality of blood stream infection. It should be early detected in blood stream infection for intervention.