RESEARCH ON CLINICAL CHARACTERISTICS AND LABORATORY TESTING IN PREGNANT WOMEN WITH MEASLES

Tóm tắt

Objectives: To investigate clinical characteristics and laboratory testing in pregnant women with measles.

Subjects and methods: 49 pregnant female patients were diagnosed with measles and were treated at the National Hospital of Tropical Diseases from 1/2018 to 12/2019. Descriptive and cross-sectional study.

Result: The mean age, parity, and gestational age of the 49 pregnant women with measles were 28.76 ± 0.59 years (21 - 29), 1.91 ± 0,12 (1 - 4), 21.24 ± 1.3 weeks (6 - 39), respectively. All patients were febrile, of which 98% patient had temperature from 38oC upwards. Every patient had erythema (87.8% typical measles rash). The cough was found in 85.7% patients, in which dry cough occupied 50%. Runny nose, Koplic’s spots, and conjunctivitis were all accounted for 30.6%. There was 28.6% diarrhea. The number of leukocytes above 10G/L was found in 8.2% patients; the rate of lymphocytes < 25% took up 89.8%; thrombopenia (< 150) constituted 30.6%. Enzyme AST and ALT >= 40IU/L were responsible for 38.8%, 44.9% respectively. 13 cases had obstetric complications (4 miscarriage, 2 stillbirths, 2 premature birth, 3 threatened to miscarry, 3 threatened preterm birth).

Conclusion: Pregnant women are possible to get measles at any age, gestational age, any time of year. The clinical characteristics and laboratory tests in pregnant women with measles are similar to those of measles in adults. Pregnant women with measles can be subject to obstetric complications such as miscarriage, stillbirth, and preterm birth.