SURVEY OF HEPATITIS B SURFACE ANTIBODY CONCENTRATION IN PATIENTS EXAMINED AND TREATED AT THE CENTER FOR TROPICAL DISEASES-BACH MAI HOSPITAL

Nguyen Van Dung1,, Truong Thai Phuong2, Nguyen Vu Hong Van3, Le Thi Huyen4, Nguyen Thi Lan Anh5
1 Center for Tropical Diseases - Bach Mai Hospital
2 Microbiology Department - Bach Mai Hospital
3 General medicine Department - Tam Anh Hospital
4 National Hospital of Tropical Diseases
5 National Institute of Hygiene and Epidemiology

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Tóm tắt

Objectives: Survey of anti-HBs concentration in patients examined and treated at the Center for Tropical Diseases - Bach Mai Hospital from April 2012 to July 2020.
Subjects: 1. 024 patients who tested negative for HBsAg and were tested for anti-HBs were examined
and treated at the Center for Tropical Diseases - Bach Mai Hospital from April 2012 to July 2020; selected
by convenience sampling technique.
Methods: Cross-sectional descriptive study.
Results and conclusion: A total of 1024 patients including 708 positive anti-HBs patients (69.1%) with
an average anti-HBs concentration of 356.1 ± 400.6 IU/mL, and 90.7% with anti-HBs levels ≥ 10 IU/mL
in which 18.6% of patients have anti-HBs levels ≥ 1000 IU/mL, there was no significant difference in antiHBs levels between male and female. Among 163 patients with a history of hepatitis B vaccination, 78.5%
of patients were anti-HBspositive. Of the 268 tested foranti-HBc total, the positive anti-HBc total rate was
22.1% (17 patients) out of 77 negative anti-HBs patient.

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