CLINICAL AND PARACLINICAL CHARACTERISTICS OF FASCIOLIASIS PATIENTS IN THE PERIOD OF 2019 - 2023

Tóm tắt

Objectives: To describe the clinical andparaclinical characteristics of Fasciola infected patients .
Subjets and methods: Cross-sectional descriptive study on 128 patients diagnosed with fascioliasis from January 2019 to June 2023 treated at National Hospital for Tropical Diseases and National Institute of Malariology, Parasitology and Entomology.
Results: Clinical symptoms: Right upper quadrant pain accounted for 74.2%, followed by epigastric pain (44.5%), fatigue and loss of appetite (43.8%), weight loss (42.2%), fever (39.8%) and hepatomegaly (7%). Paraclinical findings: Hypereosinophilia accounted for 75%, elevation of AST and ALT accounted for
12.5% and 24.2%, respectively. 91% of patients were positive with anti-fasciola antibodies by ELISA testing, 24% of them had fasciola’s eggs in stool. 100% of patients had liver lesions on ultrasound, of which 62.5% were found in the right liver. The lesions sized from 3 - 5,9 cm in 35.9% and from 6 - 8,9 cm in 38.3% of patients.
Conclusions: Clinical and paraclinical characteristics of patients infected with fascioliasis are very diverse. Diagnosis should be based on the combination of clinical features, hypereosinophilia, fasciola antibodies and ultrasound images.