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Ngày xuất bản: 15/12/2023
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DOI: https://doi.org/10.59873/vjid.v4i44.334
Số xuất bản
Tập 4 Số 44 (2023): Vietnam Journal of Infectious Diseases
Chuyên mục
Nghiên cứu khoa học
Trích dẫn bài báo
Nguyen, D. D., Vu, M. D., & Bui, V. H. (2023). CLINICAL AND SUB-CLINICAL CHARACTERISTICS OF MENINGITIS CAUSED BY VARICELLA ZOSTER VIRUS. Tạp chí Truyền nhiễm Việt Nam, 4(44), 73-80. https://doi.org/10.59873/vjid.v4i44.334

CLINICAL AND SUB-CLINICAL CHARACTERISTICS OF MENINGITIS CAUSED BY VARICELLA ZOSTER VIRUS

Nguyen Dinh Dung1,, Vu Minh Dien2, Bui Vu Huy1
1 Hanoi Medical University
2 National Hospital for Tropical Diseases

Nội dung chính của bài viết

Tóm tắt

Encephalitis - meningitis today is still a serious public health problem with a high mortality rate.
Objectives: To describe the clinical and subclinical characteristics of encephalitis-meningitis caused by Varicella zoster virus (VZV) in people from 15 years old.
Material and methods: A retrospective descriptive research on 40 patients with encephalitis-meningitis diagnosed based on positive VZV PCR results in cerebrospinal fluid treated at the National Hospital of Tropical Diseases and Bach Mai Hospital from January 2020 to June 2023.
Results: Common clinical manifestations of VZV meningitis are headache (90.6%), fever (59.4%), and nausea (43.8%). Common manifestations of encephalitis are behavioral and language disorders (75%), and fever (50%). In the cerebrospinal fluid, the median number of white blood cells in the two meningitis and encephalitis groups were 235.5 (100 - 440) cells/mL and 157 (46 - 497) cells/mL, respectively, of which white blood cells were lymphocytes predominate, protein of the two meningitis and encephalitis groups are 1.0 (0.5 - 1.6) G/L and 2.1 (0.9 - 5.7) G/L, respectively. We can find out brain damage on CT or MRI in the temporal lobe, frontal lobe, and insula lobe. In addition, demyelinating lesions occur in 25%.

Chi tiết bài viết

Từ khóa

Meningoencephalitis, Varicella zoster, Herpes zoster

Tài liệu tham khảo

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