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CHARACTERISTICS OF ANTIBIOTIC RESISTANCE AND TREATMENT OUTCOMES OF S. AUREUS BACTERIA AT NATIONAL HOSPITAL FOR TROPICAL DISEASES IN PERIOD FROM 2022 TO 2024
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Overview: S. aureus bacteremia (SAB) progresses severely, can lead to septic shock and death. S .aureus
is increasingly resistant to antibiotics. Updating antibiotic resistance characteristics and treatment outcomes
of S. aureus bacteremia helps doctors provide appropriate treatment.
Objectives: study to describe the antibiotic resistance characteristics of S. aureus and evaluate the treatment
outcomes of S. aureus bacteremia patients at the National Hospital for Tropical Diseases 2022 - 2024.
Subjects and methods: The study subjects included patients ≥ 18 years old, diagnosed with S. aureus
bacteremia at the National Hospital for Tropical Diseases from April 2022 to March 2024, excluding cases with positive blood culture results for multiple etiologies. The study was a cross-sectional descriptive analysis.
All samples were selected by a convenience method. Data were analyzed and processed using SPSS22.0 software with applied algorithms.
Results and conclusions: S. aureus had a high resistance rate to many antibiotics, MRSA accounted for 88%, multi-resistant bacteria accounted for 89.24%. However, S. aureus strains were still 100% sensitive to vancomycin, linezolid, tigecycline, nitrofurantoin. The average treatment time was 17.29 ± 10.4 days and all
patients used antibiotics during the entire hospitalization. The rate of initial antibiotic prescription consistent with the antibiogram was 76.5%. Treatment results did not improve or worsened was 25.8%
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Từ khóa
S. aureus, bacteremia, antibiotic resistance
Tài liệu tham khảo
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