CHARACTERISTICS OF MONOCYTE DISTRIBUTION WIDTH IN PATIENTS DIAGNOSED WITH DENGUE FEVER AT THE NATIONAL HOSPITAL FOR TROPICAL DISEASES IN 2024
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Tóm tắt
Objectives: To evaluate the characteristics of monocyte distribution width (MDW) in patients diagnosed
with Dengue fever.
Subjects and methods: A retrospective descriptive study with convenience sampling. Location and time: at the National Hospital for Tropical Diseases from January 2024 to December 2024. Inclusion criteria: Patients aged ≥ 18 years diagnosed with Dengue fever. Exclusion criteria: Presence of comorbidities or co-/superinfection with other pathogens.
Results: Among 171 patients included in the study, 58.48% were male, with a mean age of 39. MDW gradually increased during the critical phase (days 4 - 7) and decreased during the recovery phase. There was a negative correlation between MDW and platelet count from day 4 to day 10 of the illness. No significant differences in MDW were observed across age groups or genders, but notable differences were seen among the Dengue severity classifications from days 4 to 6. The optimal MDW cut-off value on day 4 was 29.415, which could predict Dengue with warning signs and severe Dengue.
Conclusions: MDW gradually increases during the critical phase and decreases in the recovery phase, showing a negative correlation with platelet count. MDW is a predictor of disease severity in Dengue fever
Chi tiết bài viết
Từ khóa
Dengue fever, monocyte distribution width, MDW
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