KHẢO SÁT TỶ LỆ NHIỄM, MỨC ĐỘ KHÁNG THUỐC KHÁNG NẤM CỦA CANDIDA SP. GÂY NHIỄM TRÙNG ĐƯỜNG TIẾT NIỆU PHÂN LẬP ĐƯỢC TẠI BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN (1/1/2018 - 31/12/2018)

Abstract

Background: Candida sp. are considered as one of the most common cause of urinary tract infection recently.

Objectives: The study aims to determine the prevalence of infection and the antifungal resistance level of Candida sp. isolated from urine samples at Nghean General Friendship Hospital in 2018.

Subjects and methods: The research objects were Candida sp. strains associated with urinary tract infections. The study design was descriptive and retrospective cross - sectional study. Results and conclusions: Among total bacteria and fungi isolates, the prevalence of Candida sp.- related urinary tract infections accounts for 23.2% (112/483). The common identified pathogens were Candida tropicalis (85; 75.89%) and Candida albicans (15; 13.89%). The majority of Candida sp. strains were isolated from Intensive Care Unit (ICU) department. 1.1% to 6.7% of Candida sp.- related urinary tract infections were resistant to Amphotericin B and 0 to 11% of those were resistant to Fluconazole. No resistance was found against Flucytosine, Voriconazole, Micafungin and Caspofungin. Recommendations: Although the antifungal resistance level detected in this study was low, it is recommended that continuous surveillances are required to determine the favorable approach for maintaining long - term protective effect of the antifungal drugs.