INVESTIGATION OF ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI CAUSING SEPSIS AT NGHEAN FRIENDSHIP GENERAL HOSPITAL (01/01/2019 - 31/12/2019)

Anh Dao Tran, Tat Thang Tran, Đuc Phuc Nguyen, Quoc Tuan Luong, Van Thuy Nguyen, Huu Tan Nguyen, Anh Tuan Le, Huu Tuan Pham, Thi Bich Toan Nguyen, Nguyen Minh Hoa Le

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Abstract

Background: Sepsis could lead to life - threatening organ failure due to the excessive and dysfunction of immune responses from the host against the microbes. The mortality of severe septicemia and sepsis shock has been very high, up to 20 - 50% and considered as the cause of millions deaths per year worldwide.


Objective: To determine the antibiotic resistance of E. coli causing septicemia at Nghean Friendship General hospital from 01/01/2019 to 31/12/2019.


Material and Method: E. coli isolates causing septicemia strains. Retrospective and descriptive cross - sectional study. Results and Discussion: E. coli accounted for 37.40%, the highest among isolated bacteria and fungi causing sepsis. E. Coli were resistant to fluoroquinolones, cephalosporines with quite high rate (43 - 58%) and low rate against amikacin and carbapenem (2.2 - 4.9%).


Recommendation: It is recommended that the continous monitoring the antibiotic resistance of E. coli should be implemented in order to deliver reasonable and prompt solutions and maintain the effectiveness of antibiotics.

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