BÁO CÁO CA BỆNH XƠ GAN MẬT TIÊN PHÁT (PRIMARY BILIARY CHOLANGITIS)

Abstract

Objective: Identify a diagnosed case of Primary biliary cirrhosis treatment at the National Hospital of Tropical Diseases.

Subjects and methods: Describe a 71 – year - old female patient with persistent elevations of liver enzymes and cholestasis, multiple times of untreated disease. We use a liver biopsy to diagnose.

Results: 71 – year- old female patient, hospitalized patient in a condition with dark yellow eye and skin, asthenia, no hemorrhage, no fever, no abnormal and no peripheral lymph nodes. Blood tests about viral hepatitis in Vietnam (hepatitis A, B, C, E, EBV, CMV) and autoimmune hepatitis markers (ANA, DsDNA, LKM1, LC1, ASGPR, pANCA, cANCA) were both give negative results. ALP tests: 467.3 UI / l, AMA: 93.2AU/ml. MRI: no mechanical biliary obstruction, liver biopsy results of typical PBC image anatomy.

Conclusion: Primary biliary cirrhosis is a common diagnosis of biliary tract disease in the world. However, this rate in Vietnam is still very low, if primary biliary cirrhosis patients are detected early, transplantation is indicated. At the right time, the liver should live after 5 years is > 80%. Therefore, in cases of patients with persistent elevated liver enzymes and/or cholestatic jaundice, there is a close coordination between the clinician, imaging and pathologist for early diagnosis and treatment. timely for patients.