ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG, HIỆU QUẢ ĐIỀU TRỊ BỆNH NHÂN NHIỄM KHUẨN HUYẾT DO Staphylococcus aureus TẠI KHOA BỆNH NHIỆT ĐỚI BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN (2018 - 2019)

Abstract

 Background: Sepsis is an acute and severe infection causing by the presence of bacteria in the bloodstream. The mortality of sepsis shock is considered to be from 20 to 50% and Staphylococcus aureus is one of the common pathogens.

Research aim: The clinical and subclinical features and treatment outcomes of Staphylococcus aureus sepsis at tropical disease department, Nghean General Friendship hospital.

Objects and methods: Descriptive and retrospective cross - sectional study on 30 patients with confirmed Staphylococcus aureus- associated sepsis and treated at tropical diseases department, Nghean General Friendship hospital.

Results: About primary infections sites of Staphylococcus aureus, skin and mucosa lesions were the highest number, accounted for 46.7% of sepsis. The clinical features of Staphylococcus aureus - associated sepsis include: high fever, chills (60%) and tachycardia (60%). 93.3% of the patients were detected without any changes of consciousness and 100% of whom found no evidence of hypotensive episode or sepsis shock. The percentage of MRSA was 70% and the treatment outcome was 20 well-recovered and discharged patients (80%), 6.7% in severe conditions or death and 13.3% transferred to higher level hospital. Conclusion: Staphylococcus aureus associated sepsis requires early diagnosis with proper empirical antibiotic therapy in order to enhance the treatment outcome and reduce the mortality and disease complications.
Sepsis is an acute and severe infection causing by the presence of bacteria in the bloodstream. The mortality of sepsis shock is considered to be from 20 to 50% and Staphylococcus aureus is one of the common pathogens. Research aim: The clinical and subclinical features and treatment outcomes of Staphylococcus aureus sepsis at tropical disease department, Nghean General Friendship hospital. Objects and methods: descriptive and retrospective cross - sectional study on 30 patients with confirmed Staphylococcus aureus- associated sepsis and treated at tropical diseases department, Nghean General Friendship hospital. Results: About primary infections sites of Staphylococcus aureus, skin and mucosa lesions were the highest number, accounted for 46.7% of sepsis. The clinical features of Staphylococcus aureus - associated sepsis include: high fever, chills (60%) and tachycardia (60%). 93.3% of the patients were detected without any changes of consciousness and 100% of whom found no evidence of hypotensive episode or sepsis shock. The percentage of MRSA was 70% and the treatment outcome was 20 well-recovered and discharged patients (80%), 6.7% in severe conditions or death and 13.3% transferred to higher level hospital.

Conclusion: Staphylococcus aureus associated sepsis requires early diagnosis with proper empirical antibiotic therapy in order to enhance the treatment outcome and reduce the mortality and disease complications.