KHỐI CHOÁN CHỖ NỘI SỌ Ở BỆNH NHÂN NHIỄM HIV/AIDS – NGHIÊN CỨU MÔ TẢ LOẠT CA TẠI BỆNH VIỆN BỆNH NHIỆT ĐỚI

Abstract

Introduction: Approach to HIV-infected patients with intracranial mass lesions (IML) was a challenging issue of HIV/AIDS management, especially in etiological diagnosis. This study was aim to detailly describe the causes of IML in HIV-infected population as well as patient characteristics.

Subjects and methods: We performed a prospective case series research at Hospital of Tropical diseases, Ho Chi Minh city, Vietnam.

Results: In 57 patients (48 men and 9 women) with median age of 34, we found that 45.6% patients had prehistory of HIV infection and the most common risk factor was unprotected sex. Headache and fever were the most and second prevalent symptom as well as chief complain. Approximately one-half of patients had more than 2 lesions, and parietal lobe was the most commonplace location in radiology. The etiologies of IML were Toxoplasma gondii encephalitis (TE) (49.1%), tuberculoma (15.8%), cryptococcoma (3.5%) and lung carcinoma with brain metastases (1.8%), 29.8% cases could not been identify the cause of IML. We also found that low T-CD4 count and positive result of Toxoplasma gondii serology test can be anticipated with TE.

Conclusions: Toxoplasma gondii encephalitis was the most common cause of HIV-infected patients with IML and some factors such as T-CD4 count and Toxoplasma gondii serology test result could be used to support etiological diagnosis.