CĂN NGUYÊN NHIỄM KHUẨN HUYẾT VÀ MỨC ĐỘ KHÁNG KHÁNG SINH TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN NĂM 2020-2021

Abstract

Antibiotic resistance is currently a global problem, increasing due to the inappropriate use of antibiotics in many areas such as agriculture and medicine.

Objectives: Identify the bacteria that often cause sepsis and investigate the antibiotic resistance of these bacteria at Thai Nguyen National Hospital in 2020.

Method: Cross-sectional, retrospective descriptive studies.

Results: Research on 113 sepsis patients with positive blood culture, we found that: The most common cause of sepsis is Escherichia coli (33.6%), followed by Staphylococus aureus (23.9%), Klebsiella pneumonia (12.4%), Acinetobacter baumanni (10.4%).40-50% of E.coli strains were resistant or less sensitive to 3rd generation cephalosporins, the rate of resistance to colistin and carbapenem antibiotics was low (3.4% and less than 6%, respectively), 77.7% of the strains that are sensitive to amikacin.Over 50% of strains of S.aureus are resistant to oxacillin, ceftriaxone, carbapenem, over 60% are still sensitive to ceftazidime, levofloxacin, and cefepim. 63.6% of K.pneumoniae strains were resistant to fosfomycin, the rate of resistance to carbapenem and aminoside antibiotics was less than 8%. A.baumanni strains have low resistance (less than 10%) to carbapenem, aminoside, quinolone antibiotics, only 8.3% are sensitive to ceftriaxone.