SO SÁNH ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG BỆNH NHÂN VIÊM PHỔI DO VI NẤM CANDIDA VÀ ASPERGILLUS

Abstract

Objective: To compare the clinical and paraclinical characteristics between  patients  with  invasive  pulmonary fungal infection caused by Candida and Aspergillus.

Subjects and method: Cross-sectional  descriptive  study  on  105 patients   with   invasive   pulmonary   fungal   infection treated at the National Hospital for Tropical Diseases.

Results: The most common risk factor in the group of patients with Candida pneumonia was antibiotic use (80.3%), in the group of Aspergillus pneumonia was the use of corticosteroids (24.2%).

There was no statistically significant difference (p > 0.05) in the  respiratory symptoms as well as hematological tests, inflammatory bilan between the two groups by Candida and Aspergillus. The rate of cavity lesions on chest X-ray was higher in Aspergillus pneumonia group (15.2%) than in Candida pneumonia group (9.1%) with p<0.05. In the group of patients with Candida pneumonia, the rate of patients with extrapulmonarymanifestations of fungal septicemia was 3%, urinary fungal infection was 14%. There were no manifestations of organ damage other than the lungs caused by Aspergillus in the group of patients with Aspergillus pneumonia.

Conclusion: Clinically it is necessary to combine risk factors and extrapulmonary lesions in the differential diagnosis of Candida and Aspergillus pulmonary fungal infections.