ĐẶC ĐIỂM DỊCH TỄ, LÂM SÀNG, CẬN LÂM SÀNG VIÊM MÀNG NÃO DO ACINETOBACTER BAUMANNII

Abstract

Background: Acinetobacter baumannii is not only one of the most dangerous bacteria today with strong antibiotic resistance but also one of the common causes of meningitis which is related to neurosurgery, procedures or ventricular drainage. Objectives: To describe the epidemiological, clinical, laboratory characteristics and antibiotic resistance in patients with meningitis caused by A.baumannii treated at National Hospital for Tropical Diseases (NHTD).

Subjects and research methods: A retrospective combined with prospective cohort study on 29 patients diagnosed with meningitis caused by A.baumannii treated at the National Hospital for Tropical Diseases in 5 years from June 2017 to June 2022.

Results and conclusions: Meningitis caused by A.baumannii is common in men under the age of 60 who had underlying diseases, prolonged hospital stay, history of surgical intervention, neurosurgery. The prominent clinical manifestation is the increased brain and meaningeal damage after neurological interventions and more severere intoxication proved by elevated inflamatory markers. A.baumannii isolates were multi-resistant with a high rate of > 80%, of which meropenem  resistance was 96.6%.