KHẢO SÁT TÌNH HÌNH KHÁNG KHÁNG SINH CỦA CÁC VI KHUẨN GRAM ÂM ĐƯỜNG RUỘT THƯỜNG GẶP TẠI BỆNH VIỆN TỈNH NINH THUẬN

Abstract

Objectives: Determining the prevalence and antibiotic resistance of common intestinal gram-negative bacteria in the Ninh Thuan Provincial General Hospital.

Subjects, materials and methods: Analytical cross-sectional description. Take 583 cultures with intestinal gram-negative bacteria strains isolated at Ninh Thuan Provincial General Hospital from October 1, 2019 to September 30, 2020.

Results: Specimen isolates of intestinal gram-negative bacteria from sputum (18.4%), fluid (4.1%), blood (28.1%), pus (39.3%), urine (10, first %). Intestinal gram-negative bacteria were isolated in 46% male, 54% female with the age ratio: < 40 years old 17.7%, 40 to 60 years old 46.8%, > 60 years old 35.5%; Escherichia coli accounted for 57.1%, Klebsiella spp. 34.5%, Enterobacter spp. 0.9%, Proteus spp. 7.5%.

Conclusions: Intestinal gram-negative bacteria are more than 50% resistant to commonly used antibiotics such as ciprofloxacin, cefoperazone, ceftriaxone, doxycyline, gentamycin, kanamycin, levofloxacine. Use Imipenem and meropenem in monotherapy. in addition, other drugs such as: netilmicin, amikacin, cefoxitin can be used in the combination regimen.