ĐẶC ĐIỂM MỘT SỐ CHỈ SỐ SINH HÓA VÀ HUYẾT HỌC Ở NGƯỜI BỆNH SỐT XUẤT HUYẾT DENGUE ĐIỀU TRỊ TẠI TRUNG TÂM Y TẾ THÀNH PHỐ NAM ĐỊNH NĂM 2022

Abstract

Objectives: To characterize some biochemical indices (AST, ALT) and hematology (WBC, PLT, Hct) in patients with Dengue fever when hospitalized for treatment at Nam Dinh City Medical Center since from January to December 2022, Determine the relationship between the change of some biochemical and hematological indicators with disease severity in patients with Dengue hemorrhagic fever treated at Nam Dinh City Medical Center from January to December 2022.
Subjects and methods: 270 Dengue fever patients treated at Nam Dinh City Medical Center from January
2022 to December 2022. cross-sectional descriptive study.
Results: Dengue disease was found in all ages and in both men and women. Mainly encountered patients with dengue (80.4%), Dengue with DHF was 17.4% and severe Dengue accounted for 2.2%. On admission, the average AST concentration was 56.5 U/L, the average ALT concentration was 38 U/L, the white blood
cell count was 3.6 G/L, Hct 40.1 ± 3.84%, platelet 121.5 ± 47.5 G/L. In the dangerous stage: There is a
relationship between the level of leukopenia, platelets and the increase of Hct, AST, ALT with the severity of dengue disease.
Conclusions: Characteristics of AST, ALT and leukocyte, platelet, and Hct indexes upon admission and the relationship between the level of leukopenia, platelets and the elevation of Hct, AST, ALT at the dangerous stage of the disease with the severity of dengue is the basis for the control, treatment and prognosis of the disease.