CLINICAL AND SUBCLINICAL CHARACTERISTICS OF THE PATIENTS WITH DENGUE HEMORRHAGIC FEVER THAI NGUYEN

Quynh Nga Luong Thu1,, Van Thanh Duong1, Thi Tuyet Nguyen1
1 Thai Nguyen University of Medicine and Pharmacy

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Abstract

Objectives: Describe clinical and subclinical characteristics of patients with dengue hemorrhagic fever (DHF) in Thai Nguyen.
Subjects and methods: Retrospective study on 43 patients diagnosed with DHF according to the standard of the Ministry of Health in 2019.
Results: The most common age was 35 - ≤ 60, accounting for 25/43 (58.1%), the least common age was ≤ 16 years old (4.6%). The mean of age was 43.6 ± 16.5; Male (55.8%) was higher proportion than female (44.2%). Patients lived in 15/21 wards and 1/11 communes in Thai Nguyen city; 4/6 districts included Phu Binh, Vo Nhai, Dai Tu and Dong Hy. Patients had fever accounted for the highest rate of 100%, followed by bleeding 31/43 (72.1%), abdominal pain or tenderness10/43 (23.2%), vomiting 7/43 (16.3%), diarrhea (9.3%), pleural effusion and acites 4.6%. Patients with hematocrit 35 - 45% accounted for the highest proportion of 21/43 (48.8%); Next, hematocrit > 45% accounted for 20/43 (46.6%). Patients with low platelets 5 - < 50 accounted for the highest
proportion of 22/43 (51.2%), followed by 20/43 (46.5%) of patients with platelets of 50 - < 150 G/L; No patient had platelets < 5 G/L. Patients with AST 40 - < 400 (U/L) accounted for the highest proportion of 35/43 (81.4%), 2/43 (4.6%) patients with AST ≥ 1000 (U/L). Patients with ALT 40 - < 400 (U/L) accounted for the highest proportion in the study 30/43 (69.8%), 1/43 (2.3%) patients had AST ≥ 1000 (U/L). 100% of patients in the study were cured and discharged from the hospital, with no deaths, of which: patients with DHF and DHF with warning signs accounted for the highest rate of 46.6%.

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