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Date Published: 25/05/2024
Abstract Views: 314
Views PDF: 167
DOI: https://doi.org/10.59873/vjid.v2i46.360
Issue
Vol. 2 No. 46 (2024)
Section
Scientific research
How to Cite
Nguyen, V. T., Dang, T. T., Bui, Q. S., N, D. L., & Pham, K. L. (2024). PREDICTIVE VALUE OF MEAN PLATELET VOLUME IN DIAGNOSIS AND PROGNOSIS OF SEPSIS IN CHILDREN. Vietnam Journal of Infectious Diseases, 2(46), 11-17. https://doi.org/10.59873/vjid.v2i46.360

PREDICTIVE VALUE OF MEAN PLATELET VOLUME IN DIAGNOSIS AND PROGNOSIS OF SEPSIS IN CHILDREN

Van Tuy Nguyen, Thi Tam Dang, Quang Su Bui, Dac Luong N, Kieu Loc Pham

Main Article Content

Abstract

Objectives: We conducted this study to determine the predictive value of mean platelet volume in predicting sepsis and predicting severe illness in children at Hue Central Hospital.
Subjects and methods: This was a cross-sectional descriptive study combined with a prospective followup of children with sepsis at the Hue Central Hospital. Logistic regression was used to assess the predictive value of blood count parameters.
Results: The study of 67 children with sepsis showed that the successful treatment rate was 82.1%. The mortality rate in children with severe sepsis or septic shock was nearly 40%. The number of neutrophils, platelets, mean platelet volume (MPV), and MPV/platelet ratio (MPVPR) were significantly different between the severity levels of sepsis. Anemia and increased MPV were risk factors for death in children with sepsis (p < 0.05). MPV had a good value in predicting mortality from sepsis with an area under the curve of 0.803, sensitivity of 100%, and specificity of 56.4%.
Conclusions: MPV has a good value in diagnosing the severity and predicting mortality from sepsis

Article Details

Keywords

Children, sepsis, mean platelet volume, prognosis

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