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Date Published: 25/05/2024
Abstract Views: 331
Views PDF: 606
DOI: https://doi.org/10.59873/vjid.v2i46.364
Issue
Vol. 2 No. 46 (2024)
Section
Scientific research
How to Cite
Phan, N. P. T., Du, T. D., Pham, T. D. H., Dao, B. K., Thanh Cong, Do Dinh Nguyen, Thi Hong Hanh, & Ho, D. T. N. (2024). ASSESSMENT OF SEPSIS-3 CRITERIA AND qSOFA IN THE DIAGNOSIS OF SEPSIS IN CIRRHOSIS. Vietnam Journal of Infectious Diseases, 2(46), 40-46. https://doi.org/10.59873/vjid.v2i46.364

ASSESSMENT OF SEPSIS-3 CRITERIA AND qSOFA IN THE DIAGNOSIS OF SEPSIS IN CIRRHOSIS

Ngoc Phuong Thao Phan, Trong Duc Du, Tran Dieu Hien Pham, Bach Khoa Dao, Thanh Cong , Do Dinh Nguyen , Thi Hong Hanh , Dang Trung Nghia Ho

Main Article Content

Abstract

Objectives: To evaluate the abilitity of Sepsis-3 criteria and qSOFA score in predicting in-hospital mortality
in patients with cirrhosis and bacterial infections.
Subjects and methods: A case series study of patients upper 18 years old with cirrhosis and bacterial infections,
treated in Hospital for Tropical Disease from May 2019 to June 2020.
Results: A total of 352 patients with cirrhosis and bacterial infections were included in our study. Frequent
type of infections are UTI (31.5%), SBP (28.7%) and pneumonia (15.5%). The major causative organisms
are gram-negative bacteria, e.g E. coli (40%), K. pneumoniae (13%) and Aeromonas spp (8%). The average
mortality was 8.8%. In the study, all patients had qSOFA score recorded but only 178/352 (50%) patients had
baseline SOFA score and ∆SOFA calculated. At the moment of antibiotic administration, qSOFA (OR = 2.04;
KTC 95% 1.29 - 3.23; p = 0.002), ∆ SOFA (OR = 1.63; KTC 95% 1.24 - 2.14; p < 0.001) has a statistically significant association with in-hospital mortality. When comparing the predictability of mortality between the two scores qSOFA (AUROC = 0.651) and ∆ SOFA (AUROC = 0.741), there were no statistically significant differences (p = 0.8).
Conclusions: With its simple, easy to use for all patient and the ability in mortaility prediction when comparing
with Sepsis-3 criteria, qSOFA can be used as a bedside tool to diagnose sepsis in cirrhotic patients without baseline SOFA.

Article Details

Keywords

Bacterial infection, sepsis, cirrhosis, Sepsis-3, qSOFA

References

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