CLINICAL FEATURE AND LABORATORY FINDING OF ADENOVIRUS PEDIATRIC PATIENTS TREATED AT THE NATIONAL HOSPITAL FOR TROPICAL DISEASES, PERIOD 2022 - 2023

Thi Thuy Dang, Thu Trang Le, Thi Kim Dinh Dao, Hai Van Nguyen, Quy Khai Truong

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Abstract

Objectives: The study aimed to describe the clinical feature and laboratory finding of Adenovirus pediatric patients treated at the National Hospital of Tropical Diseases.
Subjects and methods: Retrospective descriptive study was conducted on 125 pediatric patients ≤ 16 years old, diagnosed with Adenovirus infection, treated at National Hospital of Tropical Diseases, from June 2022 to May 2023.
Results: More male than female patients, the male/female ratio was 1.8/1. The infected age was mainly from 1 to 5 years old, accounting for 75.2%, the average age was 33.5 ± 22.6 years. Hospitalizations mainly occured in the fall and winter months. Respiratory tract infection was the most common clinical form (63.2%), followed by mixed form (26.4%) and fever, pharyngitis and conjunctivitis (10.4%). Common clinical manifestations were fever (100%), cough (93.6%), red swollen tonsils (91.2%), runny nose (80.8%), sneezing (77.6%), followed by pulmonary rales and vomiting. Lung lesions on X-ray were diverse, most lesions were diffuse on both sides (80.8%), the most common are interstitial lesions (56.0%).
Conclusions: Clinical and laboratory manifestations of Adenovirus infection were nonspecific. During epidemics, conjunctivitis and pseudomembranous tonsillitis may be suggestive of Adenovirus infection. Increased leukocytosis and CRP levels are common in Adenovirus infection.

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References

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