MANAGEMENT OF HAND FOOT AND MOUTH DISEASE WITH SEVERE COMPLICATION

Minh Tien Nguyen, Huu Nhan Nguyen, Vu Phuong Thy Le, Thi Gia Hanh Nguyen, Thanh Hong Phan, Phuoc Huu Nguyen

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Abstract

Objectives: To describe therapeutic interventions for children having hand foot mouth disease (HFMD)
with severe complication admitted at Emergency Department, Pediatric Intensive Care Unit, City Children’s hospital from May 2023 till September 2023.
Methods: Retrospective case series study.
Results and conclusions: 148 HFMD with severe complication consisted of grade 3 (74.3%), grade 4
(25.7%), mean age of 22.4 months old, most of them under 3 years (90.5%). Respiratory complication
requiring mechanical ventilation accounted for 70.3%, cardiovascular complication included cardiopulmonary collapse (14.2%), systemic arterial hypertension (35.1%). Management of HFMD with severe complication composed of early mechanical ventilation, shock resuscitation by approved standard
flowchart and continuous veno-venous hemofiltration. Average length of stay in PICU was 6.3 days, 2 case
died (1.4%) in condition of refractory shock, respiratory failure and deep coma. 
Recommendations: Modern medical instruments for respiratory, circulatory resuscitation should be equipped for province hospitals as well as high techniques such as mechanical ventilation, monitor of IBP, should be handed over in order to save more children with HFMD with severe complication.

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