ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG TAY CHÂN MIỆNG TẠI BỆNH VIỆN NHI ĐỒNG 2 NĂM 2023

Abstract

Background: After the COVID-19 pandemic, some clinicians have noted some changes in the incidence, clinical manifestations, and complications of hand and foot disease (HFMD). There is currently no research on the characteristics of pediatric HFMD patients after the COVID-19 pandemic in Vietnam.
Objectives: To describe the clinical features and laboratory findings of HFMD in children in 2023.
Methods: A cross-sectional descriptive study of HFMD cases admitted to Children's Hospital 2 in 2023.
Results: 83.6% of patients with HFMD had grade 2A, 13.2% had grade 1, 3% had grade 2B, and 0.2% had grade 4. During treatment, 52.4% of cases progressed from grade 1 to grade 2A, 38.1% from grade 2A to grade 2B, 4.8% from grade 2A to grade 4, and 4.8% from grade 2B to grade 4. The most commonly affected age group was under 60 months old (97.1%). 2.9% of patients were over 60 months old, with a higher proportion of severe cases compared to non-severe cases in this age group (p = 0.029). The most common reason for hospitalization
was fever (74.6%). Neurological complications accounted for the highest rate (98.5%), appearing most often in the first 3 days of the disease with the most common symptoms being startle (95.8%) and ataxia (10.4%). 14.5% of pediatric patients were overweight - obese. This rate was significantly higher in the severe disease group
(33.3%) than in the non-severe group (13.5%). There were 15.7% of patients with platelets over 400 K/µL, the difference between the two groups was statistically significant (p < 0.001).
Conclusions: The most common reason for hospitalization was fever. 15.1% of hospitalized children showed neurological symptoms. Children with the disease over 60 months often had severe disease. Overweight and obese children were at greater risk of serious illness. Platelets above 400 K/uL were higher in the severe disease group than in the non-severe group.