RESULTS OF HIGH FLOW NASAL CANNULA THERAPY FOR INFANTS WITH BRONCHIOLITIS

Tien Nguyen Minh, Nhan Nguyen Huu, Hanh Nguyen Thi Gia, Phuong Ho Thi Thanh, Nhan Vo Thanh, Cong Le Van

Main Article Content

Abstract

Objects: Evaluate the effectiveness of high-flow nasal cannula therapy (HFNC) in infants with bronchiolitis admitted to the emergency department of City Children's Hospital during the period from January 2024 to June 2024.
Methods: Prospective descriptive study of cases series.
Results: There were 30 children with bronchiolitis admitted to the emergency department at City Children's Hospital during the period from January 2024 - June 2024, receiving high flow nasal cannula oxygen therapy (HFNC) after failure with standard oxygen therapy, average age of 6.8 months old, and
male/female ratio: 1.1/1. Clinical manifestations before HFNC breathing included 93.3% tachypnea, 86.7% chest indrawing, 100% wheezing, 80% snoring sounds, 46.7% whistling sounds, 13.3% nostril flaring, 66.7% tachycardia, modified bronchiolitis score of 7.1 ± 1.3, SpO2 : 91.3 ± 1.5%. The results showed
improvement in infants’ respiratory failure such as tachypnea rate, chest indrawing, improved modified bronchiolitis score, SpO2, at 6 hours and 24 hours of HFNC. The successful treatment rate for HFNC was 86.7%. HFNC breathing time 48.7 ± 3.4 hours. No complications of HFNC ventilation and no deaths were documented.
Conclusions: Research shows that respiratory support with HFNC for infants with bronchiolitis failing to standard of oxygen therapy improves respiratory status as well as clinical outcomes of patients.

Article Details

References

1. Bush A, Thomson AH. Acute bronchiolitis. Bmj. 2007;335(7628):1037-41.
2. Dalziel SR, Haskell L, O'Brien S, Borland ML, Plint AC, Babl FE, et al. Bronchiolitis. The Lancet. 2022;400(10349):392-406.
3. Goebel J, Estrada B, Quinonez J, Nagji N, Sanford D, Boerth RC. Prednisolone plus albuterol versus albuterol alone in mild to moderate bronchiolitis. Clinical pediatrics. 2000;39(4):213-20.
4. Mayfield S, Bogossian F, O'Malley L, Schibler A. High‐flow nasal cannula oxygen therapy for infants with bronchiolitis: pilot study. Journal of paediatrics and child health. 2014;50(5):373-8.
5. Gadomski AM, Scribani MB. Bronchodilators for bronchiolitis. Cochrane database of systematic reviews. 2014(6).
6. Moreel L, Proesmans M. High flow nasal cannula as respiratory support in treating infant bronchiolitis: a systematic review. European journal of pediatrics. 2020;179:711-8.
7. Pedersen MB, Vahlkvist S. Comparison of CPAP and HFNC in management of bronchiolitis in infants and young children. Children. 2017;4(4):28.
8. Lin J, Zhang Y, Xiong L, Liu S, Gong C, Dai J. High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis. Archives of disease in childhood. 2019;104(6):564-76.