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CLINICAL AND SUBCLINICAL FEATURES AND TREATMENT RESULTS OF CHRONIC PANCREATITIS AT THE NATIONAL HOSPITAL FOR TROPICAL DISEASES
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Abstract
Objectives: Describe the clinical and paraclinical characteristics and treatment results of patients with chronic pancreatitis at the Central Hospital for Tropical Diseases.
Methods: The study describes 34 patients with chronic pancreatitis who were treated at the Central Hospital for Tropical Diseases from January 2021 to December 2024.
Results: The disease is more common in women than men (male/female = 3.3/1), with an average age of 46.95 ± 14.4 years (from 16 to 87 years old). Risk factors for chronic pancreatitis: alcohol abuse (67.6%), smoking (47.1%), acute pancreatitis (44.1%), and bile duct stones (14.7%). Common clinical manifestations: abdominal pain (70.6%), and abdominal distension (47.1%). Less common symptoms were: fatigue, anorexia (26.5%), loose stools, greasy stools (23.5%), hepatomegaly (29.4%), splenomegaly (20.6%), dullness on percussion in the lower region (17.6%), tenderness on costovertebral points (14.7%), nausea/vomiting (17.6%), jaundice, yellow eyes (8.8%), weight loss (5.9%). Laboratory tests: increased blood amylase (29.4%), average 158.2 ± 131.7 IU/L,
increased blood lipase (24.1%), average 65.8 ± 16.1 U/L. On ultrasound, the pancreas was completely (35.3%) or partially (26.5%), calcification of pancreatic parenchyma (76.5%), hyperechoic bands (73.5%), hyperechoic nodules (73.5%), honeycomb lesions (23.5%), pancreatic cysts (26.5%), dilated main pancreatic duct (61.8%), Increased echogenicity of the main pancreatic duct (55.9%), irregular main pancreatic duct wall (35.3%), main pancreatic duct stones (41.2%). CT scan detected pancreatic duct stones and pancreatic duct dilatation more
frequently than ultrasound.
Results: 91.2% of patients were cured, and only 3 severe patients were asked to go home (8.8%). The average hospital stay was 19.8 ± 14.3 days (8 ÷ 82). 23.5% of patients with chronic pancreatitis had complications: pancreatic cyst (20.6%), pancreatic abscess (2.9%), abdominal bleeding (2.9%).
Conclusions: Chronic pancreatitis has diverse clinical manifestations, with prominent symptoms being epigastric pain, abdominal distension, loose stools with fat, fatigue, and weight loss. On ultrasound, there were images of complete or partial fibrosis, pancreatic duct stones, pancreatic duct dilatation, and honeycomb lesions. Most patients were cured, but some had severe complications such as pancreatic cysts, pancreatic abscesses, and abdominal bleeding.
Article Details
Keywords
Chronic pancreatitis, pancreatic fibrosis, pancreatic duct stones
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