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ANTIBIOTIC RESISTANCE CHARACTERISTICS OF COMMON PATHOGENOUS BACTERIA AT NINH THUAN PROVINCIAL GENERAL HOSPITAL 2024
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Abstract
Objectives: Determine the rate of culture-positive bacteria from clinical specimens, investigate distribution of common pathogenous bacteria and its antibiotic resistance.
Subjects and methods: A cross-sectional study, data of pathogenic bacteria and antibiogram results were collected at Ninh Thuan province general hospital from January to October 2020.
Results and conclusions: A total of 1664 different patient samples were indicated for culture and 273 samples showed positive results, accounting for an overall rate of 16.4%. The number of Gram-negative bacteria isolated is significantly higher than that of Gram-positive bacteria. In the group of Gram-negative bacteria, common is the E. coli (36.1%), Klebsiella spp. (22.7%), Acinetobacter spp. (18.1%). In the group of Gram-positive bacteria, S. aureus is the dominant (77.1%). The rate of carbapenem-resistant Enterobacteriaceae (imipenem and meropenem) in E. coli ranges from 2.7 - 3.2%. Klebsiella spp. 34.6 - 44.7%. Proteus spp. 13 - 14.3%. Acinetobacter spp. and P. aeruginosa are resistant to imipenem at rates of 68.3% and 50%, respectively. The MRSA rate of this study is 92.0%, no strains of S. aureus resistant to vancomycin, linezolid and teicoplanin were detected. Carbapenem-resistant Gram-negative bacteria are
increasingly prevalent, requiring further in-depth research to elucidate the molecular mechanisms of this resistance.
Article Details
Keywords
Bacteria, Antibiotic resistance, Ninh Thuan Provincial General Hospital
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