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Date Published: 25/06/2025
Abstract Views: 42
Views PDF: 20
DOI: https://doi.org/10.59873/vjid.v2i50.467
Issue
Vol. 2 No. 50 (2025): Tạp chí Truyền nhiễm Việt Nam
Section
Scientific research
How to Cite
Nguyen, H. Q., Do, T. V. A., Do, T. D., & Luu, T. C. (2025). A SOME OF CLINICAL AND SUBCLINICAL CHARACTERISTICS IN PATIENTS INFECTED WITH EPSTEIN BARR VIRUS IN THE BONE MARROW AT BACH MAI HOSPITAL IN 2023 - 2024. Vietnam Journal of Infectious Diseases, 2(50). https://doi.org/10.59873/vjid.v2i50.467

A SOME OF CLINICAL AND SUBCLINICAL CHARACTERISTICS IN PATIENTS INFECTED WITH EPSTEIN BARR VIRUS IN THE BONE MARROW AT BACH MAI HOSPITAL IN 2023 - 2024

Hai Quan Nguyen, Thi Vinh An Do, Tien Dung Do, Thi Chinh Luu

Main Article Content

Abstract

Objectives: To characterize some clinical and subclinical features in patients with Epstein-Barr virus infection in the bone marrow.
Subjects and methods: Cross-sectional descriptive study on 71 patients with positive PCR - EBV test results in bone marrow fluid at the Center for Hematology and Blood Transfusion, Bach Mai Hospital from January 2023 to January 2024.
Results: The results were more common in patients over 60 years of age and more common in immunocompromised patients with clinical symptoms of HLH (60.6%), fever (59.2%), splenomegaly (38%) and pneumonia 38%. In terms of total peripheral blood cell analysis, up to 83.1% of patients with anemia, in the bone marrow, 100% of patients had hyperphagocytosis, 74.6% showed signs of phagocytosis and 64.3% had hyperlymphocyte.
Conclusions: Patients with EBV are found in many specialties, especially in patients with immunodeficiency of 19.7%, with common clinical symptoms of fever (59.2%), splenomegaly (39.4%) and possible severe complications such as pneumonia (38%), HLH (60.6%).

Article Details

Keywords

Epstein-Barr splint, macrophages, bone marrow biopsy

References

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