NGHIÊN CỨU ĐẶC ĐIỂM DỊCH TỄ CÁC BỆNH NHÂN ĐỒNG NHIỄM HIV/HBV TẠI MỘT SỐ ĐỊA PHƯƠNG Ở THÀNH PHỐ HỒ CHÍ MINH

Abstract

Background: HBV co-infection with HIV is quite common. People with HBV/HIV co-infection may have more liver damage, more severe disease, and a higher risk of liver cancer and death. Ho Chi Minh City is a city with a high number of people living with HIV and HIV/HBV co-infection. study on the epidemiological and clinical characteristics of people co-infected with HIV/HBV is essential.

Research objective: To survey some epidemiological characteristics of HIV/HBV co-infected patients in some districts in Ho Chi Minh City.

Subjects and methods: 69 HIV/AIDS patients aged 18 years or older with HBV co-infection, were being treated at some outpatient clinics (OPCs) in 4 districts of Ho Chi Minh City.

Results: Epidemiological characteristics of HIV/HBV co-infected patients: Age of disease 31.2 ± 8.9 years old. Male patients 95.7%, female patients 4.3%. Patients with male homosexual relationships accounted for 50.7%.

Clinical and subclinical characteristics of HIV/HBV coinfected patients: 81.2% of HIV/HBV coinfected patients had no clinical symptoms. 5.8% of patients had symptoms of pharyn’s fungus, weight loss 4.3%, the average CD4 count at hospital was 347.58 ± 225.47 cells/mm³ The initial rate of HBeAg was positive 52, 2%, negative 47.8%. The mean HBV DNA load was 4.46 ± 1.84 log10 (copies/ml). The mean AST was 37.36 ± 21.11 U/l; Mean ALT (39.19 ± 20.82 U/l).

Conclusion: Age of disease 31.2 ± 8.9 years old. Male patients 95.7%, female patients was 4.3%. Patients with male homosexual relationships 50.7%. There were 81.2% HIV/HBV co-infected patients with no clinical symptoms. The mean CD4 count on admission was 347.58 ± 225.47 cells/mm³

The initial rate of HBeAg positive was 52.2%, negative was 47.8%. The mean HBV DNA load was 4.46 ± 1.84 log10 (copies/ml). The mean AST was 37.36 ± 21.11 U/l; Mean ALT (39.19 ± 20.82 U/l).