ĐIỀU TRỊ SỐC NHIỄM KHUẨN Ở TRẺ EM TẠI KHOA CẤP CỨU HỒI SỨC BỆNH VIỆN NHI ĐỒNG THÀNH

Abstract

Objectives: To evaluate early goal directed therapy of pediatric septic shock at pediatric intensive care, City Children's Hospital, January 1^st 2018 till April. 30^th   2019.

Methods: Cases series descriptive study.  

Results: 116 children with septic shock who were diagnosed clinically and paraclinically included in study, mean age of 23.4 months old, youngest age of 5 months old, male accounting for 51.7% female 48.3%. Outcome of early goal directed therapy in treatment of pediatric septic shock after first six hours of resuscitation showed  stable hemodynamic obtaining in 72.4%, urine output ≥ 1ml/kg/hr in 60.3%, targeted CVP value in 64.6%, ScvO2 ≥ 70% in 68.3%, lactatemia ≤ 2mmol/L in 62.1%, lactate clearance ≥ 10% at T2, T6 in  68.1%, 80.2%.  Mortality in the study was 20.7%.

Conclusions: Early goal directed therapy in treatment of pediatric septic shock might reduce mortality. Measures improving rate of early goal of interventional modalities included detailed protocol of management, training medical staff, technique of CVP insertion and invasive blood pressure monitor with equipment of modern means of resuscitation and surveillance of adherenceof theregimen for saving more patients with septic shock.