ETIOLOGICAL AGENTS AND ANTIBIOTIC RESISTANCE CHARACTERISTICS OF EMPYEMA PATIENS IN NATIONAL HOSPITAL OF PEDIATRICS

Thi Hong Hanh Le, Van Thuong Nguyen, Trung Thanh Dang

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Abstract

Objective: Determination of etiological agents and antibiotic resistance characteristics of Empyema in National Hospital of Pediatrics, from June 1 in 2018 to May 31 in 2021. Subjects and methods: This is cross - sectional study on 107 hospitalized children with empyema.


Results and conclusions: epidemiology: Almost ≤ 5 years old (73.8%), male gender (59.8%). Majority patient come from mountainous regions (62.8%). Etiology: S.aureus 22.4%, mycoplasma 4.7%, S.pneumonia 3.7%, HI 3.7%. Antibiotic resistance characteristics: The antibiotics resistance rates of S.aureusare nearly 100% to methicillin-resistant 91.7%.S.aureusare highly sensitive to Vancomycin and linezonid (nearly 100%). S.pneumoniaare totallyresistant to cefuroxime, cefotaxime, ceftriaxone and  sensitive to Vancomycinand Fluoroquinolon 100%. The resistance rates to antibiotics of H.influenza as following: Ampicilin, Cefuroxim, Cefixim 75%. H.influenza were highly sensitive to Ceftriaxone, Ciprofloxacin, Meropenem (100%).

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