STUDY ON CLINICAL, SUBCLINICAL CHARACTERISTICS AND FACTORS TO MEASURE EARLY RISK OF MORTALITY OF THE ACUTE-ON CHRONIC LIVER FAILURE PATIENTS WITH CHRONIC HEPATITIS B VIRUS

Ngoc Phuc Nguyen, Van Kinh Nguyen, Đinh Cuu Mai, Van Tuan Nguyen, Ngoc Anh Doi, Dieu Trang Pham, Quang Huy Nguyen, Vu Kien Dong

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Abstract

Objective: To describe the clinical, subclinical characteristics of the ACLF patients to facilitate early diagnosis and consider early to transplant.


Objects and methods: 95 Hepatitis B patients diagnosed with ACLF for hepatitis treatment from 1/2018 to 6/2020


Results and conclusions: Clinical symptoms were acute, 100% of patients appeared jaundice, some patients with rapid progression of early or early liver syndrome. Subclinical factors with clinically useful, rapid mortality prognostic values ​​such as a drop of PT (%) below 40%, a bilirubin > 300 μmol/l can help clinicians suggest early the medical treatment failure and decide to intervene in liver transplantation at the right time. The MELD score is of useful value in clinical mortality prognosis.

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