ETIOLOGY AND OUTCOMES OF VENTILATOR-ASSOCIATED PNEUMONIA PATIENTS IN INTENSIVE CARE UNIT OF NATIONAL HOSPITAL FOR TROPICAL DISEASES
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Abstract
Objectives: To determine the prevalence and outcome of VAP, as well as to determine the etiology that caused VAP.
Subjects and method: Prospective study, transcript description. Inclusion criteria were as follows: all patients ≥ 18 years of age admitted to the ICU who were intubated and ventilated for a minimum of 48 hours, had CPIS score ≥ 6 and the bronchial aspirates culture positive with ≥ 103 cfu/ml. Exclusion criteria were suspected or confirmed pneumonia onadmission.
Results: 188 eligible patients were enrolled, of which 42 patients (22.3%) were VAP, the mortality were 23.8%, the majority microorganisms isolated included: A. baumannii (65,8%), P. aeruginosa (28,9%), K. pneumoniae (23,1%), S. aureus (11,5%) và E. coli (5,8%), 10 patients (57,1%) infected with at least 2 different microorganisms. Mortality was highest in patients infected with A. baumannii, followed by infection with P. aeruginosa (39,4%), K. pneumoniae (30,3%). Conclusion: Approximately one-quarter of patients with mechanical ventilation suffered from VAP and about one in four cases of VAP death. The most common causes were A. baumannii, P. aeruginosa, K. pneumoniae and most of the strains were resistant to different kinds of carbapenem. Mortality in patients infected with A. baumannii was highest.
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Keywords
Ventilator-associated pneumonia (VAP), etiology, outcome