CÁC YẾU TỐ TIÊN LƯỢNG TỬ VONG Ở BỆNH NHÂN NHIỄM KHUẨN HUYẾT CÓ TỔN THƯƠNG THẬN CẤP

Abstract

Objectives: To determine characteristics and mortality prognostic factors in septic acute kidney injury patients.

Subjects and method: This prospective observational study was conducted in the Tropical disease department and the ICU at Cho Ray hospital recruiting septic acute kidney injury patients admitted from December 2019 to August 2020.

Results:A total of 106 patients were included. Median APACHE II score was 18.9 whereas the proportion of patients receiving appropriate antibiotics was 67.1%. The percentages of acute kidney injury stage 1, 2, 3 based on KDIGO 2012 were 15.8%, 46.0% và 38.2%, respectively. Patients whose kidney function recovered accounted for 46.1% at the time of hospital discharge. APACHE II score and antibiotics therapy inappropriateness were independently assosicated with death, given the OR of 1.11 (1.00-1.23) and 2.91 (1.00-8.45) respectively. The mortality prognostic model covering APACHE II score, SOFA score and antibiotics treatment yielded an AUC of 0.74 (0.63-0.86).
Conclusion: APACHE II score and antibiotics therapy inappropriateness were the two mortality prognostic factors in septic acute kidney injury patients.