EPIDEMIOLOGICAL AND CLINICAL CHARACTERISTIC OF SEPSIS CAUSED BY BURKHOLDERIA PSEUDOMALLEI INFECTION AT NATIONAL HOSPITAL FOR TROPICAL DISEASES FROM 2016 - 2021

Tóm tắt

Objectives: Describing the epidemiological and clinical characteristics of sepsis caused by Burkholderia pseudomallei infection at the National Hospital for Tropical Diseases.
Patients and methods: We did a cross - sectional descriptive analysis of 68 patients, diagnosis of sepsis caused by Burkholderia pseudomallei between January 2016 and July 2021 at the National Hospital for Tropical Diseases.
Results and conclusions: The mean age was 52.69 years old, mainly male (82.4%). The patients live mostly in rural areas (89.7%), who are scattered in 19 provinces in North and Central Vietnam concentrated in Ha Tinh, Thanh Hoa, Nghe An, Bac Giang and Ha Noi. The majority of occupation is farming, accounting for 52.9%. The disease mainly occurs in the rainy season from June to November (79.4%). The disease occurs mostly in patients with underlying medical conditions of which the most common is diabetes (57.4%). The duration from symptom onset to hospital admission is mainly over 7 days (75%), max 90 days. Lungs were the most commonly affected organs (63.2%). Abscess
manifestations occurred in multiple organs: lung (2.9%), spleen (20.6%), liver (7.4%), kidney (1.5%), skin (7.4%), muscle (7.4%), brain (5.9%), salivary gland (1.5%). The rate of septic shock was high 20.6%.