SURVEY OF ANTIBIOTIC RESISTANCE OF ISOLATED BACTERIAL STRAINS AT NINH THUAN PROVINCE GENERAL HOSPITAL IN 2023

Nguyen Vinh Nghi1,, Le Huy Thach1, Truong Van Hoi1, Nguyen Huynh Nhu Y1, Nguyen Thai Dang Khoa1
1 Ninh Thuan Provincial General Hospital

Nội dung chính của bài viết

Tóm tắt

Objectives: Distribution of the proportion of bacterial isolates and their antibiotic resistance rate at Ninh Thuan Provincial General Hospital (NTPGH).
Subjects and methods: All bacterial isolates from various types of clinical specimens from a departments of NTPGH from October 1, 2022 to September 30, 2023.
Methods: Cross-sectional description.
Results and conclusions: Of the 993 samples designated for culture, 988 cultured samples contained pathogenic bacteria, accounting for 99.5%. Pus specimens account for the highest rate of 32.1%; Gramnegative bacteria account for 76% while Escherichia coli was found in 324 samples, accounting for 32.8%, the highest proportion. Escherichia coli resists ampicillin, bactrim, and tetracycline at 95.4%, 90.5%, and 75.8%, respectively. Staphylococcus aureus resists penicillin, azithromycin, erythromycin, clindamycin, oxacillin, and bactrim at 96.5%, 93.5%, 93.2%, 93.2%, 81.9%, and 75.0 %, correspondingly. Acinetobacter spp. resists cefotaxime at 100%, ceftriaxone (100%), bactrim (92.3%), ceftazidime (90.9%), cefepime (87.8%), tetracycline (84.7%), gentamycin (81 .4%), ciprofloxacin (80.0%), levofloxacin (78.9%), and piperacillin-tazobactam (76.9%). Klebsiella spp. resists ampicillin, and bactrim at 99.1%, and (86.7%),
respectively.
Enterococcus spp. resists tetracycline at 85.7%. Proteus spp. resists tetracycline, bactrim, and ampicillin at 94.9%, (86.8%), and (78.3%), correspondingly. Pseudomonas aeruginosae resists ampicillinsulbactam, and ceftriaxone at 100%, and 75%, respectively.

Chi tiết bài viết

Tài liệu tham khảo

1. Nguyen Huu An, Tran Thi Tuyet Nga, Cao Huu Nghia, Vu Le Ngoc Lan (2013), Antibiotic resistance rate of Staphylococcus aureus in clinical
samples at Pasteur Institute, City. Ho Chi Minh.
2. Pham Thi Hoai An, Vu Le Ngoc Lan, Uong Nguyen Duc Minh, Phan Ngoc Thao, Cao Huu Nghia (2014), Survey on antibiotic resistance of Klebsiella Pneumoniae on specimens isolated at the Pasteur Institute, Ho Chi Minh City .
3. Van Bich, Nguyen Su Minh Tuyet, Vo Thi Tra An, Nguyen Thanh Tung (2008), Survey on antibiotic resistance of Escherichia Coli at Gia Dinh People's Hospital.
4. Tran Minh Giang, Tran Van Ngoc (2015), Determining the antibiotic resistance rate of Pseudomonas aeruginosa causing ventilator-associated pneumonia and risk factors at Gia Dinh People's Hospital.
5. Vu Ngoc Hieu, Pham Hong Nhung (2017), Antibiotic resistance levels of some common bacteria causing skin and soft tissue infections in patients with isolated diabetes at Bach Mai Hospital.
6. Cao Minh Nga, Nguyen Thi Yen Chi, Vu Bao Chau & Nguyen Thanh Bao (2013), "Antibiotic resistance of Klebsiella spp. and ESBL-producing E. coli isolated at hospital 175", Medical Journal Ho Chi Minh City,17 (1)279-285.
7. Nguyen Hoang Thu Trang (2011), Characteristics of genes encoding extended-spectrum β-lactamase in some gram-negative bacteria and the
risk of transmission via plasmids, Master's thesis in genetics, Ho Chi Minh City University of Natural Sciences Chi Minh.
8. Hanoi Medical University (2012), Clinical Pharmacology, Medical Publishing House, Hanoi.
9. Nguyen Si Tuan, Luu Tran Linh Da, Pham Van Dung, Nguyen Thuy Huong (2012), Research on antibiotic resistance models of pathogenic bacteria at
Thong Nhat Dong Nai General Hospital.
10. Chu Thi Hai Yen, Pham Thi Huynh Giao, Nguyen Thi Hieu Hoa, Tran Ngoc Thao, Ho Thi Hoa (2014), Survey on antibiotic resistance rate of bacteria
isolated at Trung Vuong Emergency Hospital.
11. Pham Hoang Yen, Ngo Thi Thi, Do Thi Minh Huyen, laboratory team of Vietnamese-French Hospital Hanoi (2016), Antibiotic resistance situation of common pathogenic bacterial strains isolated from patients came for examination and treatment at Hanoi French-Vietnamese Hospital from 11/2014 to 10/2016