THỰC TRẠNG MANG VI KHUẨN ĐA KHÁNG Ở BỆNH NHÂN THỞ MÁY ĐIỀU TRỊ TẠI KHOA HỒI SỨC TÍCH CỰC BỆNH VIỆN BỆNH NHIỆT ĐỚI TW

Abstract

Objectives: To determine the prevalence of multi-drug resistant organisms in ventilated-patients at the Intensive care unit and assess the change in this prevalence during hospitalization.

Subjects and method: Prospective, cross-sectional descriptions study. Patients ≥ 18 years old, intubation/tracheostomy mechanical ventilated, were collectedtrachea-bronchial aspiration and faeces/rectal swabs specimenson admission and at each week during hospitalization for culture on selective media to detect multidrug-resistant organisms (VRE, CRE, ESBL enterobacteriae).

Result: 189 eligible patients were enrolled in the study. On admission, 64.5% of patients carry at least 1 multi-drug resistant organism in faeces/rectal swabs and 52.5% of patients carry at least 1 multi-drug resistant organism in respiratory specimens.This rate increased gradually during the hospital stay, respectively 84.1%; 91.0%; 92.7% at week 1, 2, 3 hospitalized for faeces/rectal swabs specimens and 72.5%; 85.7%; 86.7% at week 1,2,3 for respiratory specimens. ESBL enterobacteriae account for the highest percentage.

Conclusion: More than half of patients already have at least 1 multi-drug resistant organism on admission. This rate increased gradually during the hospital stay. ESBL enterobacteriae account for the highest percentage in both faeces/rectal swabs and trachea-bronchial aspiration specimens.