ỨNG DỤNG PHẦN MỀM WHONET ĐỂ THEO DÕI TÌNH TRẠNG KHÁNG KHÁNG SINH CỦA CÁC VI KHUẨN THƯỜNG GẶP VÀ XÂY DỰNG PHÁC ĐỒ SỬ DỤNG KHÁNG SINH BAN ĐẦU TẠI BỆNH VIỆN ĐA KHOA THỐNG NHẤT ĐỒNG NAI TỪ NĂM 2020 - 2023

Abstract

Introduction: Currently in many hospitals, the rate of appropriate initial antibiotic use is not high. Therefore, antibiogram plays a very important role in the treatment of infected patients. From the analyzed
data, it can be helpful to develop hospital procedures for the use of antibiotic prophylaxis in surgery or to guide empirical antibiotic treatment.
Objectives: Monitor the antibiotic resistance situation of some common bacteria to develop guidelines for antibiotic use at Thong Nhat Dong Nai General Hospital.
Subjects and method: All bacterial strains isolated at Thong Nhat Dong Nai General Hospital from July 1, 2020 - June 30, 2023. Synthesize reports on bacterial antibiotic resistance on WHONET software.
Results and conclusions: Cumulative antibiogram was constructed presented by bacterial group, clinical block and specimen groups. The positive culture rate was 26.98% of all cultured samples. The 5 most common infectious agents were Staphylococcus aureus (23.4%), Escherichia coli (18.6%), Klebsiella pneumonia (13.3%), Acinetobacter baumannii (11.8%), and Pseudomonas aeruginosa (10.4%), accounting for 77.5% of all isolates. 34.9% were diagnosed within 48 hours of admission. These were potentially hospital-related infections. Hospital-acquired infections had higher resistance rates than community-acquired infections to most of the tested antibiotics. For colistin, the 2 strains of Klebsiella pneumonia and Pseudomonas aeruginosa had higher resistance rates to this antibiotic, 10% and 3%, respectively