CLINICAL, PARACLINICAL AND ETIOLOGY OF BLOOD STREAM INFECTION IN DIABETIC PATIENTS TREATED AT NATIONAL HOSPITAL FOR TROPICAL DISEASES, PERIOD 2016-2021

Thi Dieu Ngan Ta, Thi Hai Yen Doan, Ngoc Thach Pham

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Abstract

Objective: To describe the clinical, paraclinical and etiology of blood stream infection in diabetic patients treated at National Hospital for Tropical Diseases. Methods: A cross-sectional study on 176 diabetic patients with bloodstream infection diagnosed by positive blood culture, isolated bacteria in the first 48h of hospital admission.


Results: Of them, 39.8% had never been diagnosed with diabetes before. 74.1% of patients had blood glucose at admission ≥ 10mmol/L and 84.2% had HbA1c index ≥ 7%. 93% of patients had the fever, respiratory infection accounted for the highest percentage of all infected organs (31.3%). There were 60.8% with leukocytosis; 45.5% thrombocytopenia; 15.1% had acute kidney injury, mainly level 1 damage; 67.9% had an increase in CRP >100 mg/L and 42.4% had PCT >10 ng/ml. Gram negative-bacteria were the main cause of bloodstream infection, most common of them were E. coli (30.1%), K. pneumoniae (15.3%), B. pseudomallei (10.8%). The rate of septic shock accounted for 17.1 %, the mortality rate was 9.1%.

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